On 20-21 October 2014 the fourth European Cluster Conference, organised by the European Commission’s Directorate General for Enterprise and Industry, took place in Brussels, Belgium. The conference addressed the role of clusters in support of SME growth, industrial renewal and regional structural change and competitiveness. It gathered some 300 stakeholders, notably key policy-makers from the national and regional authorities, practitioners and high-level speakers from academia and industry. During the conference, the latest analytical findings and trends will be presented to support evidencebased policy–making. Pavla Břusková, president of the National Cluster Association, met the executives of cluster organizations who are participating in the strategic partnership NATUREEF. The Czech Republic was represented by the cluster organisation CREA& Hydro Energy in the NATUREEF.